8-PRENYLGENISTEIN
- Product Name
- 8-PRENYLGENISTEIN
- CAS No.
- 104691-86-3
- Chemical Name
- 8-PRENYLGENISTEIN
- Synonyms
- Lupiwighteone;Luncheonette;8-PRENYLGENISTEIN;8-Isopentenylgenistein;4',5,7-Trihydroxy-8-prenylisoflavone;4',5,7-Trihydroxy-8-isopentenylisoflavone;5,7-Dihydroxy-3-(4-hydroxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one;3-(4-Hydroxyphenyl)-5,7-dihydroxy-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one;5,7-Dihydroxy-3-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one,5,7-dihydroxy-3- (4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-
- CBNumber
- CB7246036
- Molecular Formula
- C20H18O5
- Formula Weight
- 338.35
- MOL File
- Mol file
8-PRENYLGENISTEIN Property
- Melting point:
- 133-135℃
- Boiling point:
- 583.5±50.0 °C(Predicted)
- Density
- 1.351±0.06 g/cm3(Predicted)
- storage temp.
- 4°C, protect from light
- solubility
- DMSO : 100 mg/mL (295.55 mM; Need ultrasonic)
- form
- Powder
- pka
- 6.62±0.20(Predicted)
N-Bromosuccinimide Price
- Product number
- L478020
- Product name
- Lupiwighteone
- Packaging
- 10mg
- Price
- $715
- Updated
- 2021/12/16
- Product number
- L478020
- Product name
- Lupiwighteone
- Packaging
- 25mg
- Price
- $1595
- Updated
- 2021/12/16
- Product number
- 9654AF
- Product name
- Lupiwighteone
- Packaging
- 10mg
- Price
- $1737
- Updated
- 2021/12/16
- Product number
- FP137754
- Product name
- 8-Prenylgenistein
- Packaging
- 25mg
- Price
- $2400
- Updated
- 2021/12/16
- Product number
- FP137754
- Product name
- 8-Prenylgenistein
- Packaging
- 5mg
- Price
- $775
- Updated
- 2021/12/16
8-PRENYLGENISTEIN Chemical Properties,Usage,Production
Uses
Lupiwighteone is a natural product derivative of Genistein (G350000). Genistein exhibits specific inhibitory activity against tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol.
Definition
ChEBI: Lupiwighteone is a member of isoflavones.
target
PARP | Bcl-2/Bax | Caspase | Akt | CDK | ROS | P450 (e.g. CYP17)